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In a very recent analyze, we noted the identification and the characterization of a whole new atypical opioid receptor with one of a kind detrimental regulatory Houses in direction of opioid peptides.1 Our benefits confirmed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a